fatigue
Anemia occurs when the kidneys stop fulfilling their secondary role of producing red blood cells. This reduction in red blood cells interferes with the delivery of oxygen and nutrients throughout the body, leading to disruption of cellular metabolism. Symptoms of anemia include extreme tiredness, nausea and fatigue.
As kidney function gradually deteriorates, the function of other systems, including the musculoskeletal system, gradually deteriorates. Dizziness, memory loss, decreased stamina, muscle cramps, bone pain and nausea are all signs of kidney problems.